Azithromycin is indicated for infections (caused by susceptible organisms) in lower respiratory tract infections including bronchitis and pneumonia, in upper respiratory tract infections including sinusitis and pharyngitis/tonsillitis, in otitis media, and in skin and soft tissue infections. In sexually transmitted diseases in men and women, Azithromycin is indicated in the treatment of non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis.
CONTRAINDICATION & PRECAUTION
Azithromycin is contraindicated in patients with a known hypersensivity to Azithromycin or any of the macrolide antibiotics. Because of the theoretical possibility of ergotism, Azithromycin and ergot derivatives should not be co-administered. As liver is the principal route of excretion of Azithromycin, it should not be used in patients with hepatic disease. Avoid concomitant administration with terfenadine or astemizole. Precaution should be taken in patients with more severe renal impairment.
Azithromycin is well tolerated with a low incidence of side effects. The side effects include nausea, vomiting, abdominal discomfort (pain / cramps), flatulence, diarrhea, headache, dizziness and skin rashes and are reversible upon discontinuation of therapy.